[PDF.94et] Data-driven modeling of molecular interactions at the trans-Golgi network of mammalian cells
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Data-driven modeling of molecular interactions at the trans-Golgi network of mammalian cells
Patrick Weber
[PDF.dq16] Data-driven modeling of molecular interactions at the trans-Golgi network of mammalian cells
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| 2015-07-20 | Original language:English | PDF # 1 | .0 x.0 x.0l,.0 | File type: PDF | 125 pages|
In this thesis simulation models have been developed and validated to investigate the protein-lipid interaction mechanisms at the trans-Golgi network (TGN) of mammalian cells. In two systems biological studies, ordinary differential equation models were used to examine the interactions between the lipids involved in the sphingomyelin synthase 1 reaction at the TGN and the proteins involved in the regulation of non-vesicular Endoplasmic reticulum to TGN ceramide transfer....
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